| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM220882 |
|---|
| Substrate/Competitor | US9302986, benzylamine |
|---|
| Meas. Tech. | MAO-B Inhibition Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | >10000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Deodhar, M; Findlay, AD; Foot, JS; Jarolimek, W; Mcdonald, IA; Robertson, AD; Turner, CI Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof US Patent US9302986 Publication Date 4/5/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM220882 |
|---|
| US9302986, benzylamine |
|---|
| Name | BDBM220882 |
|---|
| Synonyms: | US9302986, 33 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H19FN2O3S |
|---|
| Mol. Mass. | 302.365 |
|---|
| SMILES | CC(C)NS(=O)(=O)c1ccc(OC\C(CN)=C/F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
