| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Ligand | BDBM220884 |
|---|
| Substrate/Competitor | US9302986, benzylamine |
|---|
| Meas. Tech. | DAO Inhibition Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | <100±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Deodhar, M; Findlay, AD; Foot, JS; Jarolimek, W; Mcdonald, IA; Robertson, AD; Turner, CI Substituted 3-haloallylamine inhibitors of ASSAO and uses thereof US Patent US9302986 Publication Date 4/5/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Name: | Amiloride-sensitive amine oxidase [copper-containing] |
|---|
| Synonyms: | ABP | ABP1 | AOC1 | AOC1_HUMAN | Amiloride-binding protein | DAO | DAO1 | Diamine oxidase | Diamine oxidase (DAO) | Histaminase | KAO | Kidney amine oxidase |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 85387.64 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P19801 |
|---|
| Residue: | 751 |
|---|
| Sequence: | MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
|
|
|
|---|
| BDBM220884 |
|---|
| US9302986, benzylamine |
|---|
| Name | BDBM220884 |
|---|
| Synonyms: | US9302986, 18 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H17FN2O2 |
|---|
| Mol. Mass. | 252.2847 |
|---|
| SMILES | CN(C)C(=O)c1ccc(OC\C(CN)=C/F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
