Reaction Details |
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Target | Sphingosine 1-phosphate receptor 1 |
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Ligand | BDBM221916 |
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Substrate/Competitor | n/a |
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Meas. Tech. | β-Arrestin Assay |
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Temperature | 298.15±n/a K |
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EC50 | 27±n/a nM |
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Comments | extracted |
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Citation | Zhang, X; Wang, E; Guo, J; Niu, S; Dai, Z; Zheng, N; Ji, L; Wang, Z; Liang, T Heterocyclic group contained amino-methanol derivative, and salt, synthetic method and use thereof US Patent US9315492 Publication Date 4/19/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Sphingosine 1-phosphate receptor 1 |
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Name: | Sphingosine 1-phosphate receptor 1 |
Synonyms: | Edg1 | Lpb1 | S1PR1_MOUSE | S1pr1 | Sphingosine 1-phosphate receptor 1 | Sphingosine 1-phosphate receptor 1 (S1P1) |
Type: | Enzyme |
Mol. Mass.: | 42663.66 |
Organism: | Mus musculus (Mouse) |
Description: | O08530 |
Residue: | 382 |
Sequence: | MVSTSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIM
GWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSH
PQKDDGDNPETIMSSGNVNSSS
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BDBM221916 |
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n/a |
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Name | BDBM221916 |
Synonyms: | US9315492, 15 |
Type | Small organic molecule |
Emp. Form. | C21H23N3O3 |
Mol. Mass. | 365.4256 |
SMILES | COc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(N)(CO)Cc2c1 |
Structure |
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