| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM221923 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | β-Arrestin Assay |
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| Temperature | 298.15±n/a K |
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| EC50 | 354±n/a nM |
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| Comments | extracted |
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| Citation |  Zhang, X; Wang, E; Guo, J; Niu, S; Dai, Z; Zheng, N; Ji, L; Wang, Z; Liang, T Heterocyclic group contained amino-methanol derivative, and salt, synthetic method and use thereof US Patent US9315492 Publication Date 4/19/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | Edg1 | Lpb1 | S1PR1_MOUSE | S1pr1 | Sphingosine 1-phosphate receptor 1 | Sphingosine 1-phosphate receptor 1 (S1P1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42663.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | O08530 |
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| Residue: | 382 |
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| Sequence: | MVSTSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIM
GWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSH
PQKDDGDNPETIMSSGNVNSSS
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| BDBM221923 |
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| n/a |
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| Name | BDBM221923 |
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| Synonyms: | US9315492, 24 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31N3O3 |
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| Mol. Mass. | 421.5319 |
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| SMILES | CC(C)Oc1ccc(cc1C)-c1nnc(o1)-c1ccc2CCC(CO)(Cc2c1)N(C)C |
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| Structure | 
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