| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM222428 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Carbonic Anhydrase II Kinetic Assay |
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| pH | 7.4±n/a |
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| Ki | 2.35e+3±n/a nM |
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| Comments | extracted |
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| Citation |  Iqbal, S; Saleem, M; Azim, MK; Taha, M; Salar, U; Khan, KM; Perveen, S; Choudhary, MI Carbohydrazones as new class of carbonic anhydrase inhibitors: Synthesis, kinetics, and ligand docking studies. Bioorg Chem72:89-101 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA2 | CAH2_BOVIN | Carbonic anhydrase | Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29115.93 |
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| Organism: | Bos taurus |
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| Description: | n/a |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
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| BDBM222428 |
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| n/a |
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| Name | BDBM222428 |
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| Synonyms: | N'',N'''-Bis[(E)-(4-nitrophenyl)methylidene]carbonic dihydrazide (1) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N6O5 |
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| Mol. Mass. | 356.293 |
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| SMILES | [O-][N+](=O)c1ccc(\C=N\NC(=O)N\N=C\c2ccc(cc2)[N+]([O-])=O)cc1 |
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| Structure | 
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