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TargetEnoyl-[acyl-carrier-protein] reductase [NADH]
LigandBDBM223193
Substrate/Competitorn/a
Meas. Tech.Inhibition Kinetics Assay
pH8±0
Temperature298.15±0 K
Ki 44±0 nM
Citation Neckles, CEltschkner, SCummings, JEHirschbeck, MDaryaee, FBommineni, GRZhang, ZSpagnuolo, LYu, WDavoodi, SSlayden, RAKisker, CTonge, PJ Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase. Biochemistry56:1865-1878 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Enoyl-[acyl-carrier-protein] reductase [NADH]
Name:Enoyl-[acyl-carrier-protein] reductase [NADH]
Synonyms:Enoyl-ACP reductase (FabI1)
Type:Enzyme
Mol. Mass.:27824.56
Organism:Burkholderia pseudomallei
Description:Q3JG55
Residue:253
Sequence:
MRLQHKRGLIIGIANENSIAFGCARVMREQGAELALTYLNEKAEPYVRPLAQRLDSRLVV
PCDVREPGRLEDVFARIAQEWGQLDFVLHSIAYAPKEDLHRRVTDCSQAGFAMAMDVSCH
SFIRVARLAEPLMTNGGCLLTVTFYGAERAVEDYNLMGPVKAALEGSVRYLAAELGPRRI
RVHALSPGPLKTRAASGIDRFDALLERVRERTPGHRLVDIDDVGHVAAFLASDDAAALTG
NVEYIDGGYHVVG
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  Blast E-value cutoff:
BDBM223193
n/a
NameBDBM223193
Synonyms:PT409
TypeSmall organic molecule
Emp. Form.C14H13NO4
Mol. Mass.259.2573
SMILESCCc1ccc(Oc2ccccc2[N+]([O-])=O)c(O)c1
Structure
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