| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 1 |
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| Ligand | BDBM50398096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calcium Flux Assay Using Fluorometric Imaging Plate Reader (FLIPR) Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 48±n/a nM |
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| Comments | extracted |
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| Citation |  Gabriel, SD; Hamilton, MM; Lucas, MC; Qian, Y; Sidduri, A N-alkyltriazole compounds as LPAR antagonists US Patent US9321738 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 1 |
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| Name: | Lysophosphatidic acid receptor 1 |
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| Synonyms: | EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41120.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92633 |
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| Residue: | 364 |
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| Sequence: | MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVC
IFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVST
WLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGA
IPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS
RHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLA
EFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSND
HSVV
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| BDBM50398096 |
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| n/a |
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| Name | BDBM50398096 |
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| Synonyms: | CHEMBL2182042 | US9321738, 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N4O4 |
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| Mol. Mass. | 456.4932 |
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| SMILES | C[C@@H](OC(=O)Nc1c(nnn1C)-c1ccc(cc1)-c1ccc(CC(O)=O)cc1)c1ccccc1 |r| |
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| Structure | 
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