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TargetLysophosphatidic acid receptor 3 (LPAR3)
LigandBDBM50398095
Substrate/Competitorn/a
Meas. Tech.Calcium Flux Assay Using Fluorometric Imaging Plate Reader (FLIPR) Assay
Temperature298.15±n/a K
IC50 2290±n/a nM
Commentsextracted
Citation Gabriel SDHamilton MMLucas MCQian YSidduri A N-alkyltriazole compounds as LPAR antagonists US Patent  US9321738 Publication Date 4/26/2016
More Info.:Get all data from this article,  Assay Method
 
Lysophosphatidic acid receptor 3 (LPAR3)
Name:Lysophosphatidic acid receptor 1/3
Synonyms:Lysophosphatidic acid receptor Edg-7
Type:Enzyme
Mol. Mass.:40149.72
Organism:Homo sapiens (Human)
Description:Q9UBY5
Residue:353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
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  Blast E-value cutoff:
BDBM50398095
n/a
NameBDBM50398095
Synonyms:CHEMBL2182043 | US9321738, 2
TypeSmall organic molecule
Emp. Form.C28H26N4O4
Mol. Mass.482.5304
SMILESC[C@@H](OC(=O)Nc1c(nnn1C)-c1ccc(cc1)-c1ccc(cc1)C1(CC1)C(O)=O)c1ccccc1 |r|
Structure
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