| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase NanB |
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| Ligand | BDBM4706 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Sialidase Assay |
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| pH | 9±n/a |
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| Ki | 3.30e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Hayre, JK; Xu, G; Borgianni, L; Taylor, GL; Andrew, PW; Docquier, JD; Oggioni, MR Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases. BMC Biochem13:19 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase NanB |
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| Name: | Neuraminidase NanB |
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| Synonyms: | Neuraminidase B (NanB) |
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| Type: | Enzyme |
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| Mol. Mass.: | 77697.72 |
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| Organism: | Streptococcus pneumoniae |
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| Description: | Q54727; spr1531 |
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| Residue: | 697 |
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| Sequence: | MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQGGSYQLNNKSIDISSL
LLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYFSIFMRDSGEIGVEIRDAQ
KGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMYVNGIEVFSETVDTFLPISNI
NGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQEVSTIPLSNPFQLIFQSGDSTQ
ANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKINIATSYSDDNGKTWSEPIFAMKFND
YEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDKKSGKTILLADVMPAGIGNNNANKADS
GFKEINGHYYLKLKKNGDNDFRYTVRENGVVYNETTNKPTNYTINDKYEVLEGGKSLTVE
QYSVDFDSGSLRERHNGKQVPMNVFYKDSLFKVTPTNYIAMTTSQNRGESWEQFKLLPPF
LGEKHNGTYLCPGQGLALKSSNRLIFATYTSGELTYLISDDSGQTWKKSSASIPFKNATA
EAQMVELRDGVIRTFFRTTTGKIAYMTSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQ
LIDGKEAVILSTPNSRSGRKGGQLVVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELP
NHHIGVLFEKYDSWSRNELHLSNVVQYIDLEINDLTK
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| BDBM4706 |
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| n/a |
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| Name | BDBM4706 |
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| Synonyms: | (2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid | 2,3-didehydro-2-deoxy-N-acetylneuraminic acid | CHEMBL96712 | DANA | Neu5Ac2en |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17NO8 |
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| Mol. Mass. | 291.2546 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O |r,c:7| |
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| Structure | 
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