| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM225033 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| IC50 | 1.2±n/a nM |
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| Citation |  Wang, H; Cee, VJ; Herberich, BJ; Jackson, CL; Lanman, BA; Nixey, T; Pettus, LH; Reed, AB; Wu, B; Wurz, R; Tasker, A Azole compounds as PIM inhibitors US Patent US9321756 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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| BDBM225033 |
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| n/a |
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| Name | BDBM225033 |
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| Synonyms: | US9321756, 300 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N6O2 |
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| Mol. Mass. | 376.4118 |
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| SMILES | CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3cc(=O)[nH]c(n3)C3CC3)c2c1 |
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| Structure | 
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