| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 2 |
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| Ligand | BDBM8037 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | OctetRed_Method3 |
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| KOFF | 1.42E+00 s-1 |
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| Citation |  D3R, DD CSAR CDK2-CyclinA D3R D3R Publication Date 6/30/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cyclin-dependent kinase 2 |
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| Name: | Cyclin-dependent kinase 2 |
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| Synonyms: | CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 33938.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24941 |
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| Residue: | 298 |
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| Sequence: | MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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| BDBM8037 |
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| n/a |
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| Name | BDBM8037 |
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| Synonyms: | 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 8 | 4-(2,4-Dimethylthiazol-5-yl)pyrimidin-2-ylamine | 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine | 4-(dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine, 1 | CS12 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H10N4S |
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| Mol. Mass. | 206.268 |
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| SMILES | Cc1nc(C)c(s1)-c1ccnc(N)n1 |
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| Structure | 
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