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TargetCHK1_Kinase
LigandBDBM225362
Substrate/Competitorn/a
Meas. Tech.33P-Radiometric_Method1
Ki 4.38±n/a nM
Citation D3R DD Abbott CHK1 Kinase D3R  221 Publication Date 6/30/2015
More Info.:Get all data from this article,  Assay Method
 
CHK1_Kinase
Name:CHK1_Kinase
Synonyms:n/a
Type:n/a
Mol. Mass.:32109.16
Organism:Homo sapiens (Human)
Description:n/a
Residue:279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKM
LNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYL
HGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKR
REFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLAL
LHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
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  Blast E-value cutoff:
BDBM225362
n/a
NameBDBM225362
Synonyms:Chk1_104
TypeSmall Organic Molecule
Emp. Form.C29H27N3O3
Mol. Mass.465.543
SMILESOC1CCC(CC1)NC(=O)c1ccc-2c(Cc3c-2n[nH]c3-c2ccc(cc2)-c2ccc(O)cc2)c1 |(-8.72,1.74,;-7.22,1.4,;-6.17,2.52,;-4.67,2.17,;-4.22,.7,;-5.27,-.43,;-6.77,-.08,;-2.72,.35,;-1.67,1.47,;-2.11,2.94,;-.17,1.12,;.28,-.35,;1.78,-.7,;2.83,.42,;2.39,1.89,;3.65,2.77,;4.88,1.84,;4.37,.39,;5.6,-.54,;6.86,.34,;6.42,1.81,;7.35,3.04,;6.75,4.46,;7.68,5.69,;9.21,5.5,;9.8,4.08,;8.88,2.85,;10.14,6.73,;9.54,8.14,;10.47,9.37,;12,9.18,;12.92,10.41,;12.59,7.76,;11.66,6.53,;.89,2.24,)|
Structure
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