| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase SYK [355-635] |
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| Ligand | BDBM225517 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SYK assay_HTRF |
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| IC50 | 0.412±n/a nM |
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| Citation |  D3R, DD GSK SYK Kinase D3R D3R Publication Date 6/30/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Tyrosine-protein kinase SYK [355-635] |
|---|
| Name: | Tyrosine-protein kinase SYK [355-635] |
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| Synonyms: | KSYK_HUMAN | SYK | SYK Kinase |
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| Type: | n/a |
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| Mol. Mass.: | 32610.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43405[355-635] |
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| Residue: | 281 |
|---|
| Sequence: | PEEIRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALK
DELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIEL
VHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKW
PVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCP
AGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
|
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|
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| BDBM225517 |
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| n/a |
|---|
| Name | BDBM225517 |
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| Synonyms: | GTC000226A | GTC000226B |
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| Type | Small Organic Molecule |
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| Emp. Form. | C21H21N7O3S |
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| Mol. Mass. | 451.502 |
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| SMILES | OCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12 |
|---|
| Structure | 
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