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TargetIsoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A)
LigandBDBM7460
Substrate/Competitorn/a
Meas. Tech.Surface Plasmon Resonance (SPR) Assay
pH4±n/a
Kd 8.9e+3±n/a nM
Commentsextracted
Citation Ko, CC; Chen, YJ; Chen, CT; Liu, YC; Cheng, FC; Hsu, KC; Chow, LP Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells. J Biol Chem289:22078-89 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A)
Name:Isoform A1-A of Heterogeneous nuclear ribonucleoprotein A1 (A1-A)
Synonyms:HNRNPA1 | HNRPA1 | Heterogeneous nuclear ribonucleoprotein A1 (A1-A) | Heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) | ROA1_HUMAN
Type:Protein
Mol. Mass.:34206.88
Organism:Homo sapiens (Human)
Description:P09651-2
Residue:320
Sequence:
MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV
TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH
LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA
LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS
GDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPR
NQGGYGGSSSSSSYGSGRRF
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  Blast E-value cutoff:
BDBM7460
n/a
NameBDBM7460
Synonyms:2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | CHEMBL50 | Quercetin | Quercetin (10) | Quercetin (21) | Quercetin (Qur) | US11021454, Compound Quercetin | US9180183, Quercetin | med.21724, Compound 4
TypeSmall organic molecule
Emp. Form.C15H10O7
Mol. Mass.302.2357
SMILESOc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Structure
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