| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxylic ester hydrolase |
|---|
| Ligand | BDBM232998 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | BChE Inhibition Assay |
|---|
| pH | 7±0 |
|---|
| Temperature | 298.15±0 K |
|---|
| Ki | 5.0±0.8 nM |
|---|
| Citation |  Chiou, SY; Huang, CF; Yeh, SJ; Chen, IR; Lin, G Stereoselective inhibition of butyrylcholinesterase by enantiomers of exo- and endo-2-norbornyl-N-n-butylcarbamates. J Enzyme Inhib Med Chem25:13-20 (2010) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxylic ester hydrolase |
|---|
| Name: | Carboxylic ester hydrolase |
|---|
| Synonyms: | BuChE | Butyrlcholinesterase (BuChE) | Butyrylcholine esterase | Butyrylcholinesterase | Butyrylcholinesterase (BChE) | Butyrylcholinesterase (BuChE) | Butyrylcholinesterase (EqBuChE) | Carboxylic ester hydrolase | butyrylcholinesterase precursor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 68842.83 |
|---|
| Organism: | Equus caballus (Horse) |
|---|
| Description: | Q9N1N9 |
|---|
| Residue: | 602 |
|---|
| Sequence: | MQSWGTIICIRILLRFLLLWVLIGNSHTEEDIIITTKNGKVRGMNLPVLGGTVTAFLGIP
YAQPPLGRLRFKKPQSLTKWSNIWNATKYANSCYQNTDQSFPGFLGSEMWNPNTELSEDC
LYLNVWIPAPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSMNYRVGALG
FLALSENPEAPGNMGLFDQQLALQWVQKNIAAFGGNPRSVTLFGESAGAASVSLHLLSPR
SQPLFTRAILQSGSSNAPWAVTSLYEARNRTLTLAKRMGCSRDNETEMIKCLRDKDPQEI
LLNEVFVVPYDTLLSVNFGPTVDGDFLTDMPDTLLQLGQFKRTQILVGVNKDEGTAFLVY
GAPGFSKDNNSIITRKEFQEGLKIFFPRVSEFGRESILFHYMDWLDDQRAENYREALDDV
VGDYNIICPALEFTKKFSELGNDAFFYYFEHRSTKLPWPEWMGVMHGYEIEFVFGLPLER
RVNYTKAEEILSRSIMKRWANFAKYGNPNGTQSNSTRWPVFKSTEQKYLTLNTESPKVYT
KLRAQQCRFWTLFFPKVLELTGNIDEAEREWKAGFHRWNNYMMDWKNQFNDYTSKKESCS
DF
|
|
|
|---|
| BDBM232998 |
|---|
| n/a |
|---|
| Name | BDBM232998 |
|---|
| Synonyms: | (R)-(+)-endo-2-norbornyl-N-n-butylcarbamate | rac-(±)-endo-2-norbornyl carbamate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H21NO2 |
|---|
| Mol. Mass. | 211.3006 |
|---|
| SMILES | CCCCNC(=O)OC1CC2CCC1C2 |TLB:7:8:11.12:14| |
|---|
| Structure | 
|
|---|
Search and Browse
