Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGlutathione S-transferase P
LigandBDBM50140172
Substrate/Competitorn/a
Meas. Tech.GST Assay
IC50 6.9e+4±n/a nM
Citation Mangoyi, RHayeshi, RNgadjui, BNgandeu, FBezabih, MAbegaz, BRazafimahefa, SRasoanaivo, PMukanganyama, S Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products. J Enzyme Inhib Med Chem25:854-62 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glutathione S-transferase P
Name:Glutathione S-transferase P
Synonyms:FAEES3 | GST class-pi | GST3 | GSTP1 | GSTP1-1 | GSTP1_HUMAN | Glutathione S-transferase | Glutathione S-transferase (GST) | Glutathione S-transferase P | Glutathione S-transferase Pi | Glutathione transferase (GST)
Type:Enzyme
Mol. Mass.:23353.53
Organism:Homo sapiens (Human)
Description:P09211
Residue:210
Sequence:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGD
LTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYV
KALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAY
VGRLSARPKLKAFLASPEYVNLPINGNGKQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50140172
n/a
NameBDBM50140172
Synonyms:CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Table 1, Compound 21: curcumin
TypeSmall organic molecule
Emp. Form.C21H20O6
Mol. Mass.368.3799
SMILESCOc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: