| Reaction Details |
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 | Report a problem with these data |
| Target | Seed linoleate 9S-lipoxygenase-3 |
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| Ligand | BDBM234364 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Lipoxygenase Activity Assay |
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| pH | 9±n/a |
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| Temperature | 274.15±n/a K |
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| Ki | 33150±n/a nM |
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| IC50 | 11400±600 nM |
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| Comments | extracted |
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| Citation |  Sadeghian, H; Seyedi, SM; Attaran, N; Jabbari, A; Jafari, Z Synthesis and SAR comparative studies of 2-allyl-4-methoxy-1-alkoxybenzenes as 15-lipoxygenase inhibitors. J Enzyme Inhib Med Chem26:238-44 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Seed linoleate 9S-lipoxygenase-3 |
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| Name: | Seed linoleate 9S-lipoxygenase-3 |
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| Synonyms: | 15-Lipoxygenase (SLO) | LOX1.3 | LOX3 | LOX3_SOYBN |
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| Type: | Enzyme |
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| Mol. Mass.: | 96760.05 |
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| Organism: | Glycine max (Soybean) |
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| Description: | P09186 |
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| Residue: | 857 |
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| Sequence: | MLGGLLHRGHKIKGTVVLMRKNVLHVNSVTSVGGIIGQGLDLVGSTLDTLTAFLGRPVSL
QLISATKADANGKGKLGKATFLEGIITSLPTLGAGQSAFKINFEWDDGSGILGAFYIKNF
MQTEFFLVSLTLEDIPNHGSIHFVCNSWIYNAKLFKSDRIFFANQTYLPSETPAPLVKYR
EEELHNLRGDGTGERKEWERVYDYDVYNDLGDPDKGENHARPVLGGNDTFPYPRRGRTGR
KPTRKDPNSESRSNDVYLPRDEAFGHLKSSDFLTYGLKSVSQNVLPLLQSAFDLNFTPRE
FDSFDEVHGLYSGGIKLPTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKSAWMT
DEEFAREMLAGVNPNLIRCLKEFPPRSKLDSQVYGDHTSQITKEHLEPNLEGLTVDEAIQ
NKRLFLLGHHDPIMPYLRRINATSTKAYATRTILFLKNDGTLRPLAIELSLPHPQGDQSG
AFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVV
HPIYKLLHPHYRDTMNINGLARLSLVNDGGVIEQTFLWGRYSVEMSAVVYKDWVFTDQAL
PADLIKRGMAIEDPSCPHGIRLVIEDYPYAVDGLEIWDAIKTWVHEYVFLYYKSDDTLRE
DPELQACWKELVEVGHGDKKNEPWWPKMQTREELVEACAIIIWTASALHAAVNFGQYPYG
GLILNRPTLSRRFMPEKGSAEYEELRKNPQKAYLKTITPKFQTLIDLSVIEILSRHASDE
VYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLP
SSKEGLTFRGIPNSISI
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| BDBM234364 |
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| n/a |
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| Name | BDBM234364 |
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| Synonyms: | 2-Allyl-1- tert-butoxy-4-methoxybenzene (4h) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H20O2 |
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| Mol. Mass. | 220.3074 |
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| SMILES | COc1ccc(OC(C)(C)C)c(CC=C)c1 |
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| Structure | 
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