| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM235778 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Reception Binding Assay |
|---|
| Temperature | 303.15±n/a K |
|---|
| Ki | 3.7±n/a nM |
|---|
| IC50 | 7.22±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Liu, H; Xie, X; Zhen, X; Sun, H; Li, J; Zhu, L; Li, Z; Chen, Y; Jiang, H; Chen, K Hexahydrodibenzo[a,g]quinolizine compound, preparation method thereof, pharmaceutical composition and use thereof US Patent US9359372 Publication Date 6/7/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49303.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21728 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
|
|
|
|---|
| BDBM235778 |
|---|
| n/a |
|---|
| Name | BDBM235778 |
|---|
| Synonyms: | US9359372, DC037030 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23NO4 |
|---|
| Mol. Mass. | 341.4009 |
|---|
| SMILES | COc1cc2CCN3Cc4c(OC)ccc(OC)c4C[C@H]3c2cc1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
