| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Disintegrin and metalloproteinase domain-containing protein 9 |
|---|
| Ligand | BDBM113588 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 9254±n/a nM |
|---|
| Citation |  Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics US Patent US9365529 Publication Date 6/14/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Disintegrin and metalloproteinase domain-containing protein 9 |
|---|
| Name: | Disintegrin and metalloproteinase domain-containing protein 9 |
|---|
| Synonyms: | ADAM9 | ADAM9_HUMAN | Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) | KIAA0021 | MCMP | MDC9 | MLTNG |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 90567.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13443 |
|---|
| Residue: | 819 |
|---|
| Sequence: | MGSGARFPSGTLRVRWLLLLGLVGPVLGAARPGFQQTSHLSSYEIITPWRLTRERREAPR
PYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPNIQNHCHYRGYV
EGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNK
DIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMI
LLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRHDS
AQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDG
RDCSCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNK
LVDAGEECDCGTPKECELDPCCEGSTCKLKSFAECAYGDCCKDCRFLPGGTLCRGKTSEC
DVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPKDCF
IEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPSRGTKC
WGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDASVLNYDCDVQKKCHGHGVCNSNK
NCHCENGWAPPNCETKGYGGSVDSGPTYNEMNTALRDGLLVFFFLIVPLIVCAIFIFIKR
DQLWRSYFRKKRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPREVPIYANRFAVPTYAA
KQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT
|
|
|
|---|
| BDBM113588 |
|---|
| n/a |
|---|
| Name | BDBM113588 |
|---|
| Synonyms: | US8633196, 18 | US9365529, 18 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H34FN5O5S |
|---|
| Mol. Mass. | 607.696 |
|---|
| SMILES | Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(F)cc3)CC2)C(=O)NO)c2ccccc2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
