| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal Pro-X carboxypeptidase |
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| Ligand | BDBM235953 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Activity Assay |
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| pH | 5.5±n/a |
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| IC50 | 0.035±n/a nM |
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| Comments | extracted |
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| Citation |  Hale, JJ; Jiang, J; Shen, D; Shi, Z; Shu, M; Wu, Z; Yang, C Prolylcarboxypeptidase inhibitors US Patent US9365539 Publication Date 6/14/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Lysosomal Pro-X carboxypeptidase |
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| Name: | Lysosomal Pro-X carboxypeptidase |
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| Synonyms: | Angiotensinase C | Lysosomal carboxypeptidase C | PCP | PCP_HUMAN | PRCP | Proline carboxypeptidase | Prolylcarboxypeptidase | Prolylcarboxypeptidase (PRCP) |
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| Type: | Enzyme |
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| Mol. Mass.: | 55805.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P42785 |
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| Residue: | 496 |
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| Sequence: | MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
MKNWIRDFYDSAGKQH
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| BDBM235953 |
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| n/a |
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| Name | BDBM235953 |
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| Synonyms: | US9365539, 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28FN5O2 |
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| Mol. Mass. | 485.5526 |
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| SMILES | COC(=O)C(CN1CCC(CC1)c1cc(nn1-c1ncccn1)-c1ccc(F)cc1)c1ccccc1 |
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| Structure | 
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