Reaction Details |
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Target | Suppressor of tumorigenicity 14 protein [596-855] |
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Ligand | BDBM236493 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition Enzymatic Assay |
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pH | 7.4±n/a |
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Temperature | 298.15±n/a K |
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Ki | 0.088±0.01 nM |
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Comments | extracted |
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Citation | Richter, M; Leduc, R; Colombo, E; Marsault, E Matriptase inhibitors and uses thereof against orthomyxoviridae infections US Patent US9365853 Publication Date 6/14/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Suppressor of tumorigenicity 14 protein [596-855] |
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Name: | Suppressor of tumorigenicity 14 protein [596-855] |
Synonyms: | Matriptase | PRSS14 | SNC19 | ST14 | ST14_HUMAN | TADG15 |
Type: | Enzyme |
Mol. Mass.: | 28561.29 |
Organism: | Homo sapiens (Human) |
Description: | amino acids 596-855 |
Residue: | 260 |
Sequence: | GSDEKDCDCGLRSFTRQARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAA
HCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALL
ELEKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTT
CENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNK
PGVYTRLPLFRDWIKENTGV
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BDBM236493 |
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n/a |
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Name | BDBM236493 |
Synonyms: | US10988505, Comparative #2 | US9365853, 4 |
Type | Small organic molecule |
Emp. Form. | C21H30N8O4S |
Mol. Mass. | 490.579 |
SMILES | C[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1 |r| |
Structure |
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