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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gag-Pol polyprotein [489-587,Q496K] | ||
| Ligand | BDBM293270 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition of HIV Replication | ||
| pH | 7.55±n/a | ||
| EC50 | 545±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kadow, JF; Naidu, BN; Tu, Y Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication US Patent US10106504 Publication Date 10/23/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Gag-Pol polyprotein [489-587,Q496K] | |||
| Name: | Gag-Pol polyprotein [489-587,Q496K] | ||
| Synonyms: | HIV-1 Protease Chain A | HIV-1 Protease NL4-3 | POL_HV1N5 | gag-pol | ||
| Type: | Enzyme Subunit | ||
| Mol. Mass.: | 10823.26 | ||
| Organism: | Human immunodeficiency virus type 1 | ||
| Description: | P12497[489-587,Q496K] | ||
| Residue: | 99 | ||
| Sequence: |
| ||
| BDBM293270 | |||
| n/a | |||
| Name | BDBM293270 | ||
| Synonyms: | US10106504, Example 7 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H36FNO5 | ||
| Mol. Mass. | 521.6196 | ||
| SMILES | CCOc1ccc(cc1)-c1c(C)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1-c1cc(F)c2OCCCc2c1C |r,wD:16.17,(-7.47,-3.26,;-5.93,-3.26,;-5.16,-1.93,;-3.62,-1.93,;-2.85,-.59,;-1.31,-.59,;-.54,-1.93,;-1.31,-3.26,;-2.85,-3.26,;.8,-2.7,;.8,-4.24,;-.54,-5.01,;2.13,-5.01,;3.46,-4.24,;4.8,-5.01,;3.46,-2.7,;4.8,-1.93,;4.8,-.39,;6.13,.38,;7.47,-.39,;6.13,1.92,;7.47,1.15,;6.13,-2.7,;7.47,-1.93,;6.13,-4.24,;2.13,-1.93,;2.13,-.39,;3.46,.38,;3.46,1.92,;4.8,2.69,;2.13,2.69,;2.13,4.24,;.8,5.01,;-.54,4.24,;-.54,2.69,;.8,1.92,;.8,.38,;-.54,-.39,)| | ||
| Structure | 
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