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TargetGag-Pol polyprotein [489-587,Q496K]
LigandBDBM293278
Substrate/Competitorn/a
Meas. Tech.Inhibition of HIV Replication
pH7.55±n/a
EC50<100±n/a nM
Commentsextracted
Citation Kadow, JFNaidu, BNTu, Y Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication US Patent US10106504 Publication Date 10/23/2018
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587,Q496K]
Name:Gag-Pol polyprotein [489-587,Q496K]
Synonyms:HIV-1 Protease Chain A | HIV-1 Protease NL4-3 | POL_HV1N5 | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10823.26
Organism:Human immunodeficiency virus type 1
Description:P12497[489-587,Q496K]
Residue:99
Sequence:
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM293278
n/a
NameBDBM293278
Synonyms:US10106504, Example 15
TypeSmall organic molecule
Emp. Form.C41H46FNO7
Mol. Mass.683.8048
SMILESCc1nc(COC2CCOCC2)c(-c2ccc(OCCc3ccc(F)cc3)cc2)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Structure
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