Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGag-Pol polyprotein [489-587,Q496K]
LigandBDBM293317
Substrate/Competitorn/a
Meas. Tech.Inhibition of HIV Replication
pH7.55±n/a
EC50 8.00±n/a nM
Commentsextracted
Citation Kadow, JFNaidu, BNTu, Y Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication US Patent US10106504 Publication Date 10/23/2018
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587,Q496K]
Name:Gag-Pol polyprotein [489-587,Q496K]
Synonyms:HIV-1 Protease Chain A | HIV-1 Protease NL4-3 | POL_HV1N5 | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10823.26
Organism:Human immunodeficiency virus type 1
Description:P12497[489-587,Q496K]
Residue:99
Sequence:
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM293317
n/a
NameBDBM293317
Synonyms:US10106504, Example 54
TypeSmall organic molecule
Emp. Form.C37H40N6O4
Mol. Mass.632.7513
SMILESCc1nc(C)c(-c2ccc3CN(CCc3c2)c2ncnc3n(C)ncc23)c(-c2ccc3OCCCc3c2)c1[C@H](OC(C)(C)C)C(O)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: