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TargetGag-Pol polyprotein [489-587,Q496K]
LigandBDBM293327
Substrate/Competitorn/a
Meas. Tech.Inhibition of HIV Replication
pH7.55±n/a
EC50<100±n/a nM
Commentsextracted
Citation Kadow, JFNaidu, BNTu, Y Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication US Patent US10106504 Publication Date 10/23/2018
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587,Q496K]
Name:Gag-Pol polyprotein [489-587,Q496K]
Synonyms:HIV-1 Protease Chain A | HIV-1 Protease NL4-3 | POL_HV1N5 | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10823.26
Organism:Human immunodeficiency virus type 1
Description:P12497[489-587,Q496K]
Residue:99
Sequence:
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM293327
n/a
NameBDBM293327
Synonyms:US10106504, Example 64
TypeSmall organic molecule
Emp. Form.C35H39N5O5
Mol. Mass.609.7147
SMILESCOc1nccc(n1)N1CCc2cc(ccc2C1)-c1c(N)nc(C)c([C@H](OC(C)(C)C)C(O)=O)c1-c1ccc2OCCCc2c1 |r|
Structure
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