| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM26188 |
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| Substrate/Competitor | 4-Nitrophenyl acetate (NPA) |
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| Meas. Tech. | Esterase Activity Assay |
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| Ki | 1.094e+4±n/a nM |
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| Citation |  Kazancioglu, EA; Güney, M; Sentürk, M; Supuran, CT Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. J Enzyme Inhib Med Chem27:880-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35037.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22748 |
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| Residue: | 312 |
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| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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| BDBM26188 |
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| 4-Nitrophenyl acetate (NPA) |
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| Name | BDBM26188 |
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| Synonyms: | α-CA inhibitor, 12 | 1,2-Dihydroxybenzene, XI | 1,2-dihydroxybenzene | CHEMBL280998 | benzene-1,2-diol | phenol derivative, 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H6O2 |
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| Mol. Mass. | 110.1106 |
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| SMILES | Oc1ccccc1O |
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| Structure | 
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