| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
|---|
| Ligand | BDBM237294 |
|---|
| Substrate/Competitor | 4-Nitrophenyl acetate (NPA) |
|---|
| Meas. Tech. | Esterase Activity Assay |
|---|
| Ki | 2.843e+4±n/a nM |
|---|
| Citation |  Kazancioglu, EA; Güney, M; Sentürk, M; Supuran, CT Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity. J Enzyme Inhib Med Chem27:880-5 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 6 |
|---|
| Name: | Carbonic anhydrase 6 |
|---|
| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35371.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P23280 |
|---|
| Residue: | 308 |
|---|
| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
|
|
|
|---|
| BDBM237294 |
|---|
| 4-Nitrophenyl acetate (NPA) |
|---|
| Name | BDBM237294 |
|---|
| Synonyms: | 1,4-Phenylene dimethanesulfonate (6) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H10O6S2 |
|---|
| Mol. Mass. | 266.291 |
|---|
| SMILES | CS(=O)(=O)Oc1ccc(OS(C)(=O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
