| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 3 |
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| Ligand | BDBM10880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Esterase Activity Assay |
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| pH | 7.4±n/a |
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| Ki | 263000±n/a nM |
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| Comments | extracted |
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| Citation |  Ekinci, D; Karagoz, L; Ekinci, D; Senturk, M; Supuran, CT Carbonic anhydrase inhibitors: in vitro inhibition of a isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids. J Enzyme Inhib Med Chem28:283-8 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 3 |
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| Name: | Carbonic anhydrase 3 |
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| Synonyms: | CA-III | CA3 | CAH3_BOVIN | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III |
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| Type: | Enzyme |
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| Mol. Mass.: | 29376.92 |
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| Organism: | Bos taurus (Cattle) |
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| Description: | Q3SZX4 |
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| Residue: | 260 |
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| Sequence: | MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHL
VHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNP
SCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPL
VRNWRPPQPIKGRIVKASFK
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| BDBM10880 |
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| n/a |
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| Name | BDBM10880 |
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| Synonyms: | AZA | AZA2 | AZM acetazolamide | Acerazolamide, AAZ | Acetazolamide | Acetazolamide (AAZ) | Acetazolamide (AZA) | Acetazolamide (AZM) | Acetazolamide, 5 | Acetazolamide, AAZ | Acetazolamide, AZA | Acetazolamide, AZM | CHEMBL20 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Sulfonamide, 1 | US10172837, Acetazolamide | US11278534, Example acetazolamide | US11535599, Example acetazolamide | sulfonamide 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H6N4O3S2 |
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| Mol. Mass. | 222.245 |
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| SMILES | CC(=O)Nc1nnc(s1)S(N)(=O)=O |
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| Structure | 
|
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