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TargetGlycogen synthase kinase-3 beta [7-25]
LigandBDBM6418
Substrate/CompetitorGSK-3 Peptide Substrate
Meas. Tech.Kinase Inhibition Assay
IC50>10000±n/a nM
Citation Kuo, GH; Prouty, C; Wang, A; Emanuel, S; Deangelis, A; Zhang, Y; Song, F; Beall, L; Connolly, PJ; Karnachi, P; Chen, X; Gruninger, RH; Sechler, J; Fuentes-Pesquera, A; Middleton, SA; Jolliffe, L; Murray, WV Synthesis and structure-activity relationships of pyrazine-pyridine biheteroaryls as novel, potent, and selective vascular endothelial growth factor receptor-2 inhibitors. J Med Chem48:4892-909 (2005) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Glycogen synthase kinase-3 beta [7-25]
Name:Glycogen synthase kinase-3 beta [7-25]
Synonyms:G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta
Type:Enzyme fragment
Mol. Mass.:1972.14
Organism:Oryctolagus cuniculus (rabbit)
Description:Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli.. Only partial sequence is available.
Residue:19
Sequence:
TTSFAESCKPVQQPSAFGS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM6418
GSK-3 Peptide Substrate
Name:GSK-3 Peptide Substrate
Synonyms:n/a
Type:Peptide
Mol. Mass.:3277.76
Organism:n/a
Description:n/a
Residue:27
Sequence:
(Biotin)KRREILSRRP(phospho)SYR-Amide