| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 2 |
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| Ligand | BDBM238307 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CA Activity Assay |
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| Ki | 175±n/a nM |
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| Citation |  Büyükkidan, N; Bülbül, M; Kasimogullari, R; Büyükkidan, B Synthesis and characterization of metal complexes of heterocyclic sulfonamide as carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem28:311-5 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 2 |
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| Name: | Carbonic anhydrase 2 |
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| Synonyms: | CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29250.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00918 |
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| Residue: | 260 |
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| Sequence: | MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
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| BDBM238307 |
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| n/a |
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| Name | BDBM238307 |
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| Synonyms: | [NiL2(H2O)2] (3) |
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| Type | Small organic molecule |
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| Emp. Form. | C50H32N14NiO12S4 |
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| Mol. Mass. | 1207.829 |
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| SMILES | NS(=O)(=O)c1nnc(s1)N1C(=O)C2=[N](N(C(=C2C(=O)c2ccccc2)c2ccccc2)c2cccc(c2)[N+]([O-])=O)[Ni]11N(C(=O)C2=[N]1N(C(=C2C(=O)c1ccccc1)c1ccccc1)c1cccc(c1)[N+]([O-])=O)c1nnc(s1)S(N)(=O)=O |c:16,50,54,t:13| |
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| Structure | 
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