| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM50095994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CA Inhibition Assay |
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| pH | 7.5±n/a |
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| Temperature | 277.15±n/a K |
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| Ki | 5.34e+3±n/a nM |
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| Comments | extracted |
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| Citation |  Bonneau, A; Maresca, A; Winum, JY; Supuran, CT Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem28:397-401 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29445.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8N1Q1 |
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| Residue: | 262 |
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| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
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| BDBM50095994 |
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| n/a |
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| Name | BDBM50095994 |
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| Synonyms: | 3-Cyano-7-hydroxycoumarin (2) | 7-Hydroxy-2-oxo-2H-chromene-3-carbonitrile | CHEMBL150302 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H5NO3 |
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| Mol. Mass. | 187.1516 |
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| SMILES | Oc1ccc2cc(C#N)c(=O)oc2c1 |
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| Structure | 
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