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TargetCarbonic anhydrase 3 (CA III)
LigandBDBM19461
Substrate/Competitorn/a
Meas. Tech.Esterase Activity Assay
pH7.4±n/a
Ki 2.21e+3± 0 nM
Commentsextracted
Citation Koz ÿEkinci DPerrone APiacente SAlankus-aliskan ÿBedir ESupuran CT Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes. J Enzyme Inhib Med Chem 28:412-7 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 3 (CA III)
Name:Carbonic anhydrase 3 (CA III)
Synonyms:CA-III | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase III
Type:Enzyme
Mol. Mass.:29376.92
Organism:Bos taurus (Cattle)
Description:Q3SZX4
Residue:260
Sequence:
MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTIL
NNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHL
VHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNP
SCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPL
VRNWRPPQPIKGRIVKASFK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM19461
n/a
NameBDBM19461
Synonyms:α-CA inhibitor, 5 | 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one | CHEMBL32571 | Naringenin | Naringenin (NAR) | naringetol | salipurpol
TypeEstrgen Antagonist
Emp. Form.C15H12O5
Mol. Mass.272.2528
SMILESOc1ccc(cc1)C1CC(=O)c2c(O)cc(O)cc2O1
Structure
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