| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
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| Ligand | BDBM23417 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Esterase Activity Assay |
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| pH | 7.4±n/a |
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| Ki | 4.36e+3±n/a nM |
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| Comments | extracted |
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| Citation |  Koz, ÿ; Ekinci, D; Perrone, A; Piacente, S; Alankus-Çaliskan, ÿ; Bedir, E; Supuran, CT Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes. J Enzyme Inhib Med Chem28:412-7 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 6 |
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| Name: | Carbonic anhydrase 6 |
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| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
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| Type: | Enzyme |
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| Mol. Mass.: | 35371.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P23280 |
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| Residue: | 308 |
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| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
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| BDBM23417 |
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| n/a |
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| Name | BDBM23417 |
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| Synonyms: | α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol | Epicatechin | L-Epicatechin | cid_72276 |
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| Type | Flavonol |
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| Emp. Form. | C15H14O6 |
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| Mol. Mass. | 290.2681 |
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| SMILES | O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r| |
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| Structure | 
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