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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Eukaryotic elongation factor 2 kinase | ||
| Ligand | BDBM293965 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase-Glo luminescent kinase assay | ||
| IC50 | 400±n/a nM | ||
| Citation |  Dodd, JH Compounds inhibiting eukaryotic elongation factor 2 kinase activity US Patent US10106552 Publication Date 10/23/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Eukaryotic elongation factor 2 kinase | |||
| Name: | Eukaryotic elongation factor 2 kinase | ||
| Synonyms: | Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase | EEF2K | EF2K_HUMAN | Eukaryotic elongation factor 2 kinase (EEF2K) | Eukaryotic elongation factor 2 kinase (eEF-2K) | Serine/threonine-protein kinase EEF2K | eEF-2 kinase | eEF-2K | ||
| Type: | Protein | ||
| Mol. Mass.: | 82116.99 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | n/a | ||
| Residue: | 725 | ||
| Sequence: |
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| BDBM293965 | |||
| n/a | |||
| Name | BDBM293965 | ||
| Synonyms: | US10106552, Compound 40 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H18N4OS2 | ||
| Mol. Mass. | 358.481 | ||
| SMILES | Cc1ncsc1-c1c2CCC(C)(C)c2nc2sc(C(N)=O)c(N)c12 |(-3.73,1.78,;-2.4,2.55,;-1.92,4.01,;-.38,4.01,;.09,2.55,;-1.15,1.64,;-1.15,.1,;-2.49,-.67,;-3.95,-.19,;-4.86,-1.44,;-3.95,-2.68,;-4.72,-4.01,;-3.18,-4.01,;-2.49,-2.21,;-1.15,-2.98,;.18,-2.21,;1.64,-2.68,;2.55,-1.44,;4.09,-1.44,;4.86,-.1,;4.86,-2.77,;1.64,-.19,;2.41,1.14,;.18,-.67,)| | ||
| Structure | 
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