Reaction Details | |||
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Target | Estrogen receptor | ||
Ligand | BDBM17292 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Luciferase Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 1.9±n/a nM | ||
Comments | extracted | ||
Citation | Yarger, JG; Nye, SH 6-substituted demethyl-estradiol derivatives as selective ER-β agonists US Patent US9422324 Publication Date 8/23/2016 | ||
More Info.: | Get all data from this article, Assay Method | ||
Estrogen receptor | |||
Name: | Estrogen receptor | ||
Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 | ||
Type: | Protein | ||
Mol. Mass.: | 66230.44 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P03372 | ||
Residue: | 595 | ||
Sequence: |
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BDBM17292 | |||
n/a | |||
Name | BDBM17292 | ||
Synonyms: | (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol | 17 beta-Estradiol | 17α-ethinylestradiol | 17beta-estradiol (E2) | CHEMBL135 | CS336 | ESTRADIOL | Estradiol-17 alpha | Ovocyclin | US9034854, E2 | US9040509, E2 | US9422324, E2 | US9561238, E2 | [2,4,6,7-3H]-17beta-estradiol | [2,4,6,7-3H]-E2 | [3H]-estradiol | [3H]]estradiol | ||
Type | Steroid | ||
Emp. Form. | C18H24O2 | ||
Mol. Mass. | 272.382 | ||
SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] | ||
Structure |