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TargetInterstitial collagenase [100-268]
LigandBDBM15236
Substrate/Competitorn/a
Meas. Tech.cd-MMP-1 Activity Assay
pH7.5±n/a
IC50 2.92e+3±n/a nM
Commentsextracted
Citation Lu, WZhu, JZou, SLi, XHuang, J The efficient expression of human fibroblast collagenase in Escherichia coli and the discovery of flavonoid inhibitors. J Enzyme Inhib Med Chem28:741-6 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Interstitial collagenase [100-268]
Name:Interstitial collagenase [100-268]
Synonyms:CLG | MMP1 | MMP1_HUMAN | Matrix metalloproteinase-1 (cd-MMP-1)
Type:Enzyme
Mol. Mass.:18886.85
Organism:Homo sapiens (Human)
Description:Catalytic domain of human MMP-1 (100-268 aa)
Residue:169
Sequence:
FVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADI
MISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHE
LGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQ
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  Blast E-value cutoff:
BDBM15236
n/a
NameBDBM15236
Synonyms:3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one | 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one | CHEMBL164 | Cannabiscetin | Myricetin | Myricetin (20) | Myricetin (Myr) | cid_5281672
TypeSmall organic molecule
Emp. Form.C15H10O8
Mol. Mass.318.2351
SMILESOc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
Structure
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