Reaction Details | |||
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Target | Tyrosine-protein phosphatase non-receptor type 1 | ||
Ligand | BDBM23197 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzymatic Assay | ||
pH | 6.5±0 | ||
Temperature | 303.15±0 K | ||
IC50 | 3.20e+3± 3.1e+2 nM | ||
Citation | Sun, LP; Ma, WP; Gao, LX; Yang, LL; Quan, YC; Li, J; Piao, HR Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors. J Enzyme Inhib Med Chem28:1199-204 (2013) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein phosphatase non-receptor type 1 | |||
Name: | Tyrosine-protein phosphatase non-receptor type 1 | ||
Synonyms: | PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B) | Protein tyrosine phosphatase-1B (PTP1B) | Protein-tyrosine phosphatase 1B | Protein-tyrosine phosphatase 1B (PTP1B) | Tyrosine-protein phosphatase non-receptor type 1 | Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) | ||
Type: | Protein phosphatase | ||
Mol. Mass.: | 49963.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Human recombinant GST-fusion PTP1B (1-435). | ||
Residue: | 435 | ||
Sequence: |
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BDBM23197 | |||
n/a | |||
Name | BDBM23197 | ||
Synonyms: | (1S,2R,4aS,6aS,6bR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid | US11660306, Example Ursolic acid | Ursolic Acid, 10 | Ursolic acid (UA) | pentacyclic triterpene compound 10 | ||
Type | Terpene | ||
Emp. Form. | C30H48O3 | ||
Mol. Mass. | 456.7003 | ||
SMILES | [H][C@@]12[C@@H](C)[C@H](C)CC[C@@]1(CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)C3CC[C@@]12C)C(O)=O |r,t:15| | ||
Structure |