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TargetAlpha-glucosidase MAL12
LigandBDBM243073
Substrate/Competitorp-Nitrophenyl-α-D-glucopyranoside (pNPG)
Meas. Tech.Inhibition Assay
pH7±n/a
Ki 1.70e+5± 0 nM
Commentsextracted
Citation Yousefi RAlavian-Mehr MMMokhtari FPanahi FMehraban MHKhalafi-Nezhad A Pyrimidine-fused heterocycle derivatives as a novel class of inhibitors for a-glucosidase. J Enzyme Inhib Med Chem 28:1228-35 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-glucosidase MAL12
Name:Alpha-glucosidase MAL12
Synonyms:α-Glucosidase | Maltase | alpha-Glucosidase (α-Glucosidase)
Type:Protein
Mol. Mass.:68084.32
Organism:Saccharomyces cerevisiae
Description:P53341
Residue:584
Sequence:
MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCP
FYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFK
ESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASR
QVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHP
NWGSHNGPRIHEYHQELHRFMKNRVKDGREIMTVGEVAHGSDNALYTSAARYEVSEVFSF
THVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADD
SPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSF
GKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFLLNESFEQGINVEQ
ESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNF
SGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
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BDBM243073
p-Nitrophenyl-α-D-glucopyranoside (pNPG)
NameBDBM243073
Synonyms:α-Gl inhibitor, C1
TypeSmall organic molecule
Emp. Form.C20H21N5O10
Mol. Mass.491.4082
SMILESOCC(O)C(O)C(O)C(O)C1c2c([nH]c(=O)[nH]c2=O)N(c2ccc(O)cc2)c2[nH]c(=O)[nH]c(=O)c12
Structure
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