| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50024354 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Trypsin Assay |
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| pH | 8.2±n/a |
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| Ki | >20000±n/a nM |
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| Comments | extracted |
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| Citation |  Chen, S; Ding, Z; Gong, G; Yan, X; Huang, W; Guo, F; Duan, B; Gao, R; Zhou, P; Lu, X; Dong, G Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof US Patent US10106557 Publication Date 10/23/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50024354 |
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| n/a |
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| Name | BDBM50024354 |
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| Synonyms: | CHEMBL3330444 | US10106557, Compound 2 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H20ClN3O5S |
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| Mol. Mass. | 461.919 |
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| SMILES | [H][C@@]12COc3cc(ccc3N1C(=O)O[C@H]2CNC(=O)c1ccc(Cl)s1)N1CCCCC1=O |r| |
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| Structure | 
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