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TargetCoagulation factor X
LigandBDBM294042
Substrate/Competitorn/a
Meas. Tech.Rat Coagulation Factor Xa Assay
pH8.3±n/a
Ki 3.17±n/a nM
Commentsextracted
Citation Chen SDing ZGong GYan XHuang WGuo FDuan BGao RZhou PLu XDong G Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof US Patent  US10106557 Publication Date 10/23/2018
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor X
Name:Coagulation factor X
Synonyms:Coagulation factor X precursor | F10 | Factor Xa (fXa) | Stuart factor
Type:Enzyme
Mol. Mass.:54255.03
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:482
Sequence:
MESPVRLSLLYVVLASLLLPGRSVFINRERANNVLQRIRRANSFFEEIKKGNLERECVEE
ICSFEEAREVFEDNEKTTEFWNKYEDGDQCESSPCQNQGECRDGLGSYTCTCTEGFEGKN
CELFVRKLCSLDNGDCDQFCREEQNSVVCSCAKGYFLGNDGKSCLSTAPFPCGKTNKGRA
KRSVALNTSNSEPDPEDLMPDADILYPTESPSELLNLNKTEPEANSDDVIRIVGGQECKR
GECPWQALLFSDEETDGFCGGTILNEFYILTAAHCLHQAKRFKVRVGDLNTEQEDGGEMV
HEVDMIIKHNKFQRDTYDFDIAMLRLKTPITFRENVAPACLPQKDWAEATLMTQKTGIVS
GFGRTHEKGRQSKVLKMMEVPYVDRNTCRLSTSFSITQNMFCAGYDAKQEDACQGDSGGP
HVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKARVGPTSETPRLTHP
PY
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  Blast E-value cutoff:
BDBM294042
n/a
NameBDBM294042
Synonyms:US10106557, Compound 8
TypeSmall organic molecule
Emp. Form.C21H16ClN3O5S
Mol. Mass.457.887
SMILESClc1ccc(s1)C(=O)NC[C@@H]1OC(=O)N2[C@H]1COc1cc(ccc21)-n1ccccc1=O |r|
Structure
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