| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
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| Ligand | BDBM245282 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Scintillation Proximity Assay (SPA) |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 3.2±n/a nM |
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| Comments | extracted |
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| Citation |  Thibeault, C; Clark, CG; DeLucca, I; Hu, CH; Jeon, Y; Lam, PY; Qiao, JX; Yang, W; Wang, Y; Wang, TC 7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor US Patent US9428504 Publication Date 8/30/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 1 |
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| Name: | P2Y purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42090.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47900 |
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| Residue: | 373 |
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| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
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| BDBM245282 |
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| n/a |
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| Name | BDBM245282 |
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| Synonyms: | US9428504, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33F5N4O2 |
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| Mol. Mass. | 588.6113 |
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| SMILES | CC(C)(C)CN1CCC2(CN(c3c2c(ccc3O)C(F)(F)F)c2ccccc2NC(=O)Nc2ccc(F)cc2F)CC1 |
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| Structure | 
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