| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 1 |
|---|
| Ligand | BDBM245295 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| Temperature | 298.15±n/a K |
|---|
| Ki | 3.7±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Thibeault, C; Clark, CG; DeLucca, I; Hu, CH; Jeon, Y; Lam, PY; Qiao, JX; Yang, W; Wang, Y; Wang, TC 7-hydroxy-spiropipiperidine indolinyl antagonists of P2Y1 receptor US Patent US9428504 Publication Date 8/30/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 1 |
|---|
| Name: | P2Y purinoceptor 1 |
|---|
| Synonyms: | ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42090.25 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47900 |
|---|
| Residue: | 373 |
|---|
| Sequence: | MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL
|
|
|
|---|
| BDBM245295 |
|---|
| n/a |
|---|
| Name | BDBM245295 |
|---|
| Synonyms: | US9428504, 33 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H33ClFN5O2S |
|---|
| Mol. Mass. | 594.142 |
|---|
| SMILES | CC(C)(C)CN1CCC2(CN(c3c2c(F)ccc3O)c2ccccc2NC(=O)Nc2nc3ccc(Cl)cc3s2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
