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TargetPancreatic lipase
LigandBDBM246493
Substrate/CompetitorBDBM246504
Meas. Tech.In Vitro Pancreatic Lipase Assay
pH7.4±0
Temperature310.15±0 K
Ki 2.67e+3± 3.0e+2 nM
IC50 1.272e+4± 1.41e+3 nM
Citation Yang MHChin YWYoon KDKim J Phenolic compounds with pancreatic lipase inhibitory activity from Korean yam (Dioscorea opposita). J Enzyme Inhib Med Chem 29:1-6 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pancreatic lipase
Name:Pancreatic triacylglycerol lipase
Synonyms:PL | PTL | Pancreatic triacylglycerol lipase
Type:Enzyme
Mol. Mass.:50080.69
Organism:Sus scrofa (Pig)
Description:P00591
Residue:450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTI
TNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQ
NIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAE
PCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQK
NILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC
PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSL
FGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASK
ITVERNDGKVYDFCSQETVREEVLLTLNPC
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  Blast E-value cutoff:
BDBM246493
BDBM246504
NameBDBM246493
Synonyms:3,5-Dimethoxy-2,7-phenanthrenediol (11)
TypeSmall organic molecule
Emp. Form.C16H14O4
Mol. Mass.270.28
SMILESCOc1cc2c(ccc3cc(O)cc(OC)c23)cc1O
Structure
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