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TargetPancreatic lipase
LigandBDBM246501
Substrate/CompetitorBDBM246504
Meas. Tech.In Vitro Pancreatic Lipase Assay
pH7.4±0
Temperature310.15±0 K
Ki 2.17e+3± 7.4e+2 nM
IC50 1.108e+4± 3.50e+3 nM
Citation Yang MHChin YWYoon KDKim J Phenolic compounds with pancreatic lipase inhibitory activity from Korean yam (Dioscorea opposita). J Enzyme Inhib Med Chem 29:1-6 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pancreatic lipase
Name:Pancreatic triacylglycerol lipase
Synonyms:PL | PTL | Pancreatic triacylglycerol lipase
Type:Enzyme
Mol. Mass.:50080.69
Organism:Sus scrofa (Pig)
Description:P00591
Residue:450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTI
TNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQ
NIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAE
PCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQK
NILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC
PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSL
FGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASK
ITVERNDGKVYDFCSQETVREEVLLTLNPC
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  Blast E-value cutoff:
BDBM246501
BDBM246504
NameBDBM246501
Synonyms:(4E,6E)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-4,6-heptadien-3-one (21)
TypeSmall organic molecule
Emp. Form.C20H20O4
Mol. Mass.324.3704
SMILESCOc1cc(\C=C\C=C\C(=O)CCc2ccc(O)cc2)ccc1O
Structure
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