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TargetHistamine receptor H3
LigandBDBM247467
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
Ki 6.01±n/a nM
Citation Gao, Z Substituted phenyl cycloalkyl pyrrolidine (piperidine) spirolactams and amides, preparation and therapeutic use thereof US Patent US9453023 Publication Date 9/27/2016
More Info.:Get all data from this article,  Assay Method
 
Histamine receptor H3
Name:Histamine receptor H3
Synonyms:n/a
Type:Enzyme
Mol. Mass.:48611.84
Organism:Macaca mulatta (Rhesus macaque)
Description:Q865E1
Residue:445
Sequence:
MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTS
SAFNIVLISYDRFLSVTRAVSYRAQQGNTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAG
GPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAAGAEAGETALGGGGGGGSA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSL
AVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFR
RAFTKLLCPQKLKIQPHSSLEQCWK
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  Blast E-value cutoff:
BDBM247467
n/a
NameBDBM247467
Synonyms:US9453023, 26
TypeSmall organic molecule
Emp. Form.C22H29N3O2
Mol. Mass.367.4846
SMILESC[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2c(C)noc2C)cc1 |r|
Structure
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