| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM248142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CA Inhibition Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 6.9e+2±n/a nM |
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| Comments | extracted |
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| Citation |  Durdagi, S; Scozzafava, G; Vullo, D; Sahin, H; Kolayli, S; Supuran, CT Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies. J Enzyme Inhib Med Chem29:469-75 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29445.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q8N1Q1 |
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| Residue: | 262 |
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| Sequence: | MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKII
SNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELH
VVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNF
DLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAA
FLVSNHRPPQPLKGRKVRASFH
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| BDBM248142 |
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| n/a |
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| Name | BDBM248142 |
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| Synonyms: | Grayanotoxin III (GTX3) |
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| Type | Small organic molecule |
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| Emp. Form. | C20H34O6 |
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| Mol. Mass. | 370.4804 |
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| SMILES | C[C@@]1(O)CC23C[C@@H](O)[C@@]4(O)[C@@H](C[C@H](O)C4(C)C)[C@](C)(O)[C@@H]2CCC1[C@H]3O |r,TLB:25:24:20.22.21:3.1| |
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| Structure | 
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