Reaction Details |
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Target | Secreted chorismate mutase |
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Ligand | BDBM248167 |
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Substrate/Competitor | n/a |
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Meas. Tech. | CM Assay |
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pH | 7.5±0 |
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Temperature | 310.15±0 K |
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IC50 | 2.14e+4± 9e+2 nM |
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Citation | Alokam, R; Jeankumar, VU; Sridevi, JP; Matikonda, SS; Peddi, S; Alvala, M; Yogeeswari, P; Sriram, D Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors. J Enzyme Inhib Med Chem29:547-54 (2014) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Secreted chorismate mutase |
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Name: | Secreted chorismate mutase |
Synonyms: | Chorismate mutase (CM) | Chorismate mutase (MTB CM) | Chorismate mutase-related protein | SCMU_MYCTU |
Type: | Protein |
Mol. Mass.: | 21942.03 |
Organism: | Mycobacterium tuberculosis H37Rv |
Description: | n/a |
Residue: | 199 |
Sequence: | MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFK
WRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNP
ASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSL
YQRALTTATQSYCQALPPA
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BDBM248167 |
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n/a |
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Name | BDBM248167 |
Synonyms: | Carvacrol derivative, 10 |
Type | Small organic molecule |
Emp. Form. | C9H12O |
Mol. Mass. | 136.191 |
SMILES | CC(C)c1cccc(O)c1 |
Structure |
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