| Reaction Details |
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 | Report a problem with these data |
| Target | Fibroblast growth factor receptor 4 |
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| Ligand | BDBM50355393 |
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| Substrate/Competitor | FGFR1 substrate peptide |
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| Meas. Tech. | Biochemical Kinase Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 13±n/a nM |
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| Comments | extracted |
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| Citation |  Reynolds, D; Hao, M; Wang, J; Prajapati, S; Satoh, T; Selvaraj, A Pyrimidine FGFR4 inhibitors US Patent US9434697 Publication Date 9/6/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Fibroblast growth factor receptor 4 |
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| Name: | Fibroblast growth factor receptor 4 |
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| Synonyms: | CD_antigen: CD334 FGFR4 | FGFR-4 | FGFR4 | FGFR4_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 4 (FGFR4) | JK2 | JTK2 | TKF |
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| Type: | Protein |
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| Mol. Mass.: | 87957.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22455 |
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| Residue: | 802 |
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| Sequence: | MRLLLALLGVLLSVPGPPVLSLEASEEVELEPCLAPSLEQQEQELTVALGQPVRLCCGRA
ERGGHWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAGRYLCLARGSMIVLQNLTLITGDS
LTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTP
TIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLD
VLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSDAQPHIQWLKHIVINGSSFGADGFP
YVQVLKTADINSSEVEVLYLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLPEEDPTWTA
AAPEARYTDIILYASGSLALAVLLLLAGLYRGQALHGRHPRPPATVQKLSRFPLARQFSL
ESGSSGKSSSSLVRGVRLSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQ
VVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVC
TQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGM
QYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEA
LFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYG
LMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDASSTCSSSDS
VFSHDPLPLGSSSFPFGSGVQT
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| BDBM50355393 |
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| FGFR1 substrate peptide |
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| Name: | FGFR1 substrate peptide |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 1596.80 |
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| Organism: | Artificial Organism |
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| Description: | SEQ ID NO:1 |
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| Residue: | 14 |
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| Sequence: | |
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