| Reaction Details |
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 | Report a problem with these data |
| Target | Galactokinase |
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| Ligand | BDBM249789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | qHTS Assay |
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| IC50 | 595.1±n/a nM |
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| Citation |  Boxer, MB; Walsh, MJ; Liu, L; Tanega, CD; Shen, M; Lai, K; Tang, M; Auld, DS Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders US Patent US9447087 Publication Date 9/20/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Galactokinase |
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| Name: | Galactokinase |
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| Synonyms: | GALK | GALK1 | GALK1_HUMAN | Galactokinase | Galactokinase (GALK) | Galactose kinase |
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| Type: | Enzyme |
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| Mol. Mass.: | 42271.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51570 |
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| Residue: | 392 |
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| Sequence: | MAALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM
TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAA
PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGM
PCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRR
RQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDY
RAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA
APHAMRHIQEHYGGTATFYLSQAADGAKVLCL
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| BDBM249789 |
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| n/a |
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| Name | BDBM249789 |
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| Synonyms: | US9447087, 17 | US9447087, 57 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H17ClN4O2 |
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| Mol. Mass. | 392.838 |
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| SMILES | Clc1ccccc1C1N=C(Nc2nc3ccccc3o2)NC2=C1C(=O)CCC2 |c:24,t:9| |
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| Structure | 
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