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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Ligand | BDBM253994 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assays (DELFIA) | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 1±n/a nM | ||
| Comments | extracted | ||
| Citation |  Reiser, U 6-alkynyl-pyridine derivatives US Patent US9481673 Publication Date 11/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Baculoviral IAP repeat-containing protein 2 [256-363] | |||
| Name: | Baculoviral IAP repeat-containing protein 2 [256-363] | ||
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 12600.71 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human cIAP BIR3 domain (256-363 aa) | ||
| Residue: | 108 | ||
| Sequence: |
| ||
| BDBM253994 | |||
| n/a | |||
| Name | BDBM253994 | ||
| Synonyms: | US9481673, (S)-4 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C33H30N8O | ||
| Mol. Mass. | 554.6443 | ||
| SMILES | CN[C@@H](C)C(=O)Nc1ccc(-c2c(nc3cc(C)ccn23)-c2cncn2C)c(n1)C#Cc1ccc2c(C)nccc2c1 |r,wU:2.2,(-6,-3.32,;-7.34,-2.55,;-7.34,-1.01,;-8.67,-.24,;-6,-.24,;-6,1.3,;-4.67,-1.01,;-3.33,-.24,;-3.33,1.3,;-2,2.07,;-.67,1.3,;.67,2.07,;.67,3.61,;2.13,4.09,;3.04,2.84,;4.57,2.68,;5.19,1.27,;6.68,.88,;4.29,.03,;2.76,.19,;2.13,1.6,;-.67,4.38,;-.67,5.92,;-2.13,6.4,;-3.04,5.15,;-2.13,3.91,;-2.9,2.57,;-.67,-.24,;-2,-1.01,;.67,-1.01,;2,-1.78,;3.33,-2.55,;3.33,-4.09,;4.67,-4.86,;6,-4.09,;7.34,-4.86,;7.34,-6.4,;8.67,-4.09,;8.67,-2.55,;7.34,-1.78,;6,-2.55,;4.67,-1.78,)| | ||
| Structure | 
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